Skip to main content
  • Home
  • About
  • Faculty Experts
  • For The Media
  • Videos
  • Topics
    • Alumni
    • Events
    • Faculty
    • Library
    • Research
    • Students
    • All Topics
  • Contact
  • Submit
STEM
  • All News
  • Arts & Culture
  • Business & Economy
  • Campus & Community
  • Health & Society
  • Media, Law & Policy
  • STEM
  • Veterans
  • |
  • Alumni
  • The Peel
  • Athletics
Sections
  • All News
  • Arts & Culture
  • Business & Economy
  • Campus & Community
  • Health & Society
  • Media, Law & Policy
  • STEM
  • Veterans
  • |
  • Alumni
  • The Peel
  • Athletics
  • Home
  • About
  • Faculty Experts
  • For The Media
  • Videos
  • Topics
    • Alumni
    • Events
    • Faculty
    • Library
    • Research
    • Students
    • All Topics
  • Contact
  • Submit
STEM

Modifications of a nanoparticle can change chemical interactions with cell membranes

Wednesday, January 23, 2013, By News Staff
Share

Researchers at Syracuse University’s Department of Biomedical and Chemical Engineering at L.C. Smith College of Engineering and Computer Science are studying the toxicity of commonly used nanoparticles, particles up to one million times smaller than a millimeter that could potentially penetrate and damage cell membranes.

In a recent article published along with cover art in the leading journal Langmuir entitled “Effects of nanoparticle charge and shape anisotropy on translocation through cell membranes,” researchers Shikha Nangia, assistant professor of biomedical and chemical engineering (BMCE), and Radhakrishna Sureshkumar, Department Chair of BMCE and professor of physics, showed how simple shape and charge modifications of a nanoparticle can cause tremendous changes in the chemical interactions between the nanoparticle and a cell membrane.

Nanomaterials, which are currently being used as drug carriers, also pose a legitimate concern, since no universal standards exist to educate and fully protect those who handle these materials. Nanoparticles are comparable to chemicals in their potential threat because they could easily penetrate the skin or be inhaled.

“Nanotechnology has immense potential that is starting to be being realized; a comprehensive understanding of toxicity of nanoparticles will help develop better safe handling procedures in nanomanufacturing and nano-biotechnology” says Sureshkumar and Nangia, In addition, the toxicity levels of various nanoparticles can be used to our advantage in targeting cancer cells and absorbing radiation during cancer therapy. Nanotoxicity is becoming a major concern as the use of nanoparticles in imaging, therapeutics, diagnostics, catalysis, sensing and energy harvesting continues to grow dramatically.

This research project has taken place over the past year utilizing a state of the art 448 core parallel computer nicknamed “Prophet” housed in Syracuse University’s Green Data Center. The research was funded by the National Science Foundation.

Langmuir is a notable, interdisciplinary journal of American Chemical Society publishing articles in: colloids, interfaces, biological interfaces, nano-materials, electrochemistry and devices and applications. It can be found at: pubs.acs.org/journal/langd5.

  • Author

News Staff

  • Recent
  • ‘ADA Live!’ Focuses on Protection and Advocacy Systems for People with Disabilities
    Sunday, February 28, 2021, By News Staff
  • Hilda A. Frimpong Becomes the First Black Student to Lead Syracuse Law Review
    Saturday, February 27, 2021, By Robert Conrad
  • Important Update for Flexible Spending Accounts
    Friday, February 26, 2021, By News Staff
  • Message From Dean of Students Marianne Thomson
    Friday, February 26, 2021, By News Staff
  • CAS in Intercollegiate Athletic Advising and Support Addresses Unique Needs of College Student-Athletes
    Thursday, February 25, 2021, By Jennifer Russo

More In STEM

Aerospace Engineering Alumni Profile: George Kirby ’92

Great technology requires an equally impressive business plan supporting it. The goal is to have a company led by someone who understands what makes the company innovative and also the business and analytical skill to grow it into an industry…

Keeping SARS2 Out of the Cell

As vaccines are distributed worldwide to fight the pandemic, important research at Syracuse University may uncover ways to block it and similar viruses in the future. Alison Patteson, assistant professor of physics, and Jennifer Schwarz, associate professor of physics, recently…

Syracuse University Campus as a Laboratory Funding Now Available

The Syracuse University Campus as a Laboratory for Sustainability (CALS) program is offering up to $75,000 for faculty or student projects that advance the University’s goals of reducing greenhouse gas emissions, directly or indirectly, or through raising awareness on campus…

Biology Professor Breaks Down Science Behind Ancestry, Heritage Tests

As people celebrate Black History Month, many in and connected to the African American community may be interested in tracing more of their family history and learning about their connections to the African continent. How do you piece together your…

ECS Receives National Recognition for College’s Diversity and Inclusion Efforts

The College of Engineering and Computer Science was recently awarded bronze level status from the American Society for Engineering Education’s (ASEE) Diversity Recognition Program. The program’s goal is to help engineering, engineering technology and computing programs promote diversity, equity and…

Subscribe to SU Today

If you need help with your subscription, contact sunews@syr.edu.

Connect With Us

  • Twitter
  • Facebook
  • Instagram
  • Youtube
  • LinkedIn
Social Media Directory

For the Media

Find an Expert Follow @SyracuseUNews
  • Facebook
  • Instagram
  • Youtube
  • LinkedIn
  • @SyracuseU
  • @SyracuseUNews
  • @SUCampus
  • Social Media Directory
  • Accessibility
  • Privacy
  • Campus Status
  • Syracuse.edu
© 2021 Syracuse University News. All Rights Reserved.